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Intravenous thrombolysis in acute ischemic stroke
- Authors: Domashenko M.A.1, Maksimova M.Y.1, Kistenev B.А.1, Loskutnikov M.A.1, Konovalov R.N.1, Bryukhov V.V.1, Krotenkova M.V.1, Suslina Z.A.2
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Affiliations:
- Research Center of Neurology
- Research Centre of Neurology
- Issue: Vol 2, No 2 (2008)
- Pages: 5-12
- Section: Original articles
- URL: https://www.annaly-nevrologii.com/journal/pathID/article/view/452
- DOI: https://doi.org/10.17816/psaic452
- ID: 452
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Abstract
Strategic trend in the treatment of acute stroke resulted from thrombosis or embolization of intracerebral arteries is reperfusion of the blood flow in the ischemic area – thrombolysis. The modern methods of neuroimaging (CT and MR-angiography, diffusion and perfusion-weighted MRI, CT perfusion) play an important role in the thrombolysis decision making, as they allow to visualize the occlusion of the artery causing acute stroke, recanalization of the artery due to thrombolytic therapy, as well as the dynamics of the blood flow and metabolism in the respective brain regions. The presented clinical examples demonstrate the high efficacy of the thrombolytic treatment in acute ischemic stroke under the condition of absolute compliance with the inclusion and exclusion criteria to this therapy. The treatment of patients with acute stroke should be guided by the principles of evidence-based medicine and rely on adequate diagnostic algorithm of neuroimaging methods.
Keywords
About the authors
M. A. Domashenko
Research Center of Neurology
Author for correspondence.
Email: mdomashenko@gmail.com
Russian Federation, Moscow
Marina Yu. Maksimova
Research Center of Neurology
Email: mdomashenko@gmail.com
ORCID iD: 0000-0002-7682-6672
Russian Federation, Moscow, Volokolamskoe shosse,80
B. А. Kistenev
Research Center of Neurology
Email: mdomashenko@gmail.com
Russian Federation, Moscow
M. A. Loskutnikov
Research Center of Neurology
Email: mdomashenko@gmail.com
Russian Federation, Moscow
Rodion N. Konovalov
Research Center of Neurology
Email: mdomashenko@gmail.com
ORCID iD: 0000-0001-5539-245X
Cand. Sci. (Med.), senior researcher, Neuroradiology department
Russian Federation, 125367 Moscow, Volokolamskoye shosse, 80V. V. Bryukhov
Research Center of Neurology
Email: mdomashenko@gmail.com
Russian Federation, Moscow
Marina V. Krotenkova
Research Center of Neurology
Email: mdomashenko@gmail.com
ORCID iD: 0000-0003-3820-4554
D. Sci. (Med.), Head, Radiology department
Russian Federation, 125367, Russia, Moscow, Volokolamskoye shosse, 80Z. A. Suslina
Research Centre of Neurology
Email: mdomashenko@gmail.com
Russian Federation, Moscow
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).