Presented is a review of the literature on the problem of hypoxic-ischemic perinatal brain damage in the context of alterations of astroglial regulation of neuronal energy metabolism and mechanisms of excitotoxicity. Characteristics of energy metabolism in the developing brain responsible for specificity of its damage in perinatal period, as well as cell and molecular mechanisms of disturbances of neuron-astrocyte coupling controlling regulation of neuroplasticity are discussed.
Neuron-astroglial interactions in dysregulation of energy metabolism in perinatal ischemic brain damage
- Authors: Salmina A.B.1, Okuneva S.O.2, Taranushenko T.E.2, Fursov A.A.3, Prokopenko S.V.4, Mikhutkina S.V.2, Malinovskaya N.A.2, Tagaeva G.A.2
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Affiliations:
- Voyno-Yasenetsky Krasnoyarsk State Medical University
- Krasnoyarsk State Medical Academy
- Krasnoyarsk State Medical University
- Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
- Issue: Vol 2, No 3 (2008)
- Pages: 44-51
- Section: Reviews
- Submitted: 07.02.2017
- Published: 14.02.2017
- URL: https://www.annaly-nevrologii.com/journal/pathID/article/view/395
- DOI: https://doi.org/10.17816/psaic395
- ID: 395
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About the authors
Alla B. Salmina
Voyno-Yasenetsky Krasnoyarsk State Medical University
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
S. O. Okuneva
Krasnoyarsk State Medical Academy
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
T. E. Taranushenko
Krasnoyarsk State Medical Academy
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
A. A. Fursov
Krasnoyarsk State Medical University
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
Semen V. Prokopenko
Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
S. V. Mikhutkina
Krasnoyarsk State Medical Academy
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
N. A. Malinovskaya
Krasnoyarsk State Medical Academy
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
G. A. Tagaeva
Krasnoyarsk State Medical Academy
Author for correspondence.
Email: s.v.proc.58@mail.ru
Россия, Krasnoyarsk
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